Capsinoids (e.g., capsiate, capsaicin, the active ingredients in red pepper, are promising thermogenic chemicals that might promote fat loss.They cause a burning sensation when they touch the skin and are used in heat wraps and analgesic balms.
A French study showed that capsiate supplements (100mgs/kilogram bodyweight for 14 days)decreased abdominal fat in rats and increased ATP (energy) production. The results agree with conducted at the University of Maryland Medical school, which found that obese men and women given capsinoid supplements (6mg per day for 12 weeks) lost more abdominal fat than people taking a placebo.
The supplements were well-tolerated and had few side effects. Other studies found that capsinoids prevented fat cell growth, promoted thermogenesis, reduced hunger, triggered fat breakdown, and had a small effect on fat loss. Capsinoids may be useful ingredients in weight loss supplements. (Internal Journal of Obesity, 33: 1348-1355, 2009;American Journal of Clinical Nutrition 89: 45-50, 2009
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